4-Hydroxypyrimidine → HCID 86747307, compound

HRID 1656346Notes

Reaction equation

HRID 1656346 reaction equation
[N:1]1[CH:6]=[CH:5][C:4](=[O:7])[NH:3][CH:2]=1.[CH3:8][C:9]1([CH3:20])[O:18][C:17]2[CH:16]=[CH:15][N:14]=[CH:13][C:12]=2[CH:11]2[O:19][CH:10]12>>[CH3:8][C:9]1([CH3:20])[O:18][C:17]2[CH:16]=[CH:15][N:14]=[CH:13][C:12]=2[C@@H:11]([N:1]2[CH:6]=[CH:5][C:4](=[O:7])[N:3]=[CH:2]2)[C@@H:10]1[OH:19]

Participants

3

Reactant 2

HCID 206954-HydroxypyrimidineHCID 108560303,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine

Product 1

HCID 86747307HCID 86747307, compound

Procedure

This example was also prepared by heating an equimolar mixture of 4(3H)-pyrimidone and 3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine at 60° C. for 1 hour followed by chromatography as above.

Workup

  1. temperatureby heating

Sources & evidence

ORD record
ord-dd4e2bc0b28f4220bdd4d6584e0f263b
Source dataset
uspto-grants-1993_10
Patent number
US05254557

Reaction notes

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