Hydrochloric Acid → HCID 15035215, compound

Participants

Reaction Steps

To a solution of 6-(N,N-dimethylcarbamoylthio)-3-nitro-4-phenylquinoline (2.50 g) in dioxane (100 ml) were added 2N-NaOH (50 ml) and methanol (20 ml), and the whole was stirred for 7 hrs. at room temperature. After diluted with water, the mixture was acidified with hydrochloric acid. The precipitating crystals were collected by filtration and recrystallized from acetone to give 6-mercapto-3-nitro-4-phenylquinoline as yellow needles. Yield 1.68 g (84.0%). m.p. 160°-163° C.

Provenance & Evidence