Hydrochloric Acid → HCID 15035216, compound

Participants

Reaction Steps

To a solution of 6-mercapto-3-nitro-4-phenylquinoline (1.55 g) in dioxane (30 ml) were added a solution of potassium carbonate (1.14 g) in water (10 ml) and methyl iodide (1.17 g), and the whole was stirred for 2.5 hrs. at room temperature. After dilution with water, the mixture was acidified with hydrochloric acid, and the precipitating crystals were collected by filtration and recrystallized from acetone to give 6-methylthio-3-nitro-4-phenylquinoline as yellow needles. Yield 1.39 g (85.3%). m.p. 131°-133° C.

Provenance & Evidence