HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 1486468, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Lithium Chloride | HCID 433294 | — |
| Reactant | HCID 3813534 | HCID 3813534 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 1486468 | HCID 1486468 | 70% |
Reaction Steps
A mixture of diethyl (2-benzoyl-4-chlorophenyl)aminomethylenemalonate (7.0 g), lithium chloride (3.7 g) and dimethyl sulfoxide (70 ml) was heated for 1.5 hrs. at 180° C. The mixture was diluted with water to give ethyl 6-chloro-4-phenyl-3-quinolinecarboxylate as crystals (3.8 g, 70.0%), which was recrystallized from ethanol as needles. m.p. 123°-124° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254565 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-458175b4cdf7477f9014cd2a956c8d7e |
| Source note | uspto-grants-1993_10 |