Hydrochloric Acid → HCID 69950472, compound

Participants

Reaction Steps

Ethyl hydrogen malonate (13.7 g, 104 mmol) was added to 2-furanal (10 g, 104 mmol) and ammonium acetate (20 g, 260 mmmol) in dry ethanol. The solution was heated to reflux for 6 h. The solvent was removed in vacuo to leave an oil. To this oil, 10% HCl (250 mL) was added along with ether (100 mL). The layers were separated, extracted twice with methylene chloride, dried over Na2SO4, and the solvent removed in vacuo to give 6 g of the title compound.

Provenance & Evidence