HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Formylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 3-Carboxybenzaldehyde | HCID 12077 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Formylbenzoyl chloride | HCID 15238821 | — |
Reaction Steps
A mixture of 3-formylbenzoic acid (84 grams (g), 0.558 moles), thionyl chloride (80.5 g, 0.71 moles), and dimethylformamide (3 milliliters (ml)), in toluene (500 ml) was slowly warmed to 70° C. and stirred at that temperature for 2 hours. The toluene was eliminated in the rotavap to yield 97.7 g of 3-formylbenzoyl used in the next step as such.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254584 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-46d95efa0426405ebddd057a9f6ad69a |
| Source note | uspto-grants-1993_10 |