HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Bromomethyl)-1-methylquinolin-2(1H)-one → HCID 15641069, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Bromomethyl)-1-methylquinolin-2(1H)-one | HCID 15199065 | — |
| Reactant | HCID 20078118 | HCID 20078118 | — |
| Product | HCID 15641069 | HCID 15641069 | 68% |
Reaction Steps
Using a similar procedure to that described in Example 14, 6-bromomethyl-1-methyl-1,2-dihydroquinolin-2-one was reacted with (2RS,4SR)-4-ethyl-4-(5-fluoro-3-hydroxyphenyl)-2-methyltetrahydropyran to give (2RS,4SR)-4-ethyl-4-[5-fluoro-3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]-2-methyltetrahydropyran in 68% yield, as a foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254581 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-7b2cd5094674463ab2dfb830bb613af8 |
| Source note | uspto-grants-1993_10 |