HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epichlorohydrin → 2-Aminotetralin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 7-Benzofuranol | HCID 78515 | — |
| Reactant | 2-Methyl-1-benzofuran-5-ol | HCID 590251 | — |
| Reactant | 3-Methyl-6-hydroxybenzofuran | HCID 10855624 | — |
| Reactant | 4-Benzofuranol | HCID 11607921 | — |
| Reactant | Benzofuran-5-ol | HCID 11651159 | — |
| Reactant | 4-Hydroxy-2-methylbenzofuran | HCID 12174561 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Aminotetralin | HCID 34677 | — |
Reaction Steps
Following the procedure of Example 32, and reacting epichlorohydrin with 4-hydroxy-2-methylbenzofuran, 4-hydroxybenzofuran, 5-hydroxybenzofuran, 5-hydroxy-2-methylbenzofuran, 6-hydroxy-3-methylbenzofuran or 7-hydroxybenzofuran, in the presence of piperidine, dissolving the thus obtained raw epoxide in absolute ethanol and adding thereto an ethanol solution of 2-aminotetralin, the following compounds are obtained respectively
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254595 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-6560c8e0a13f4c05b432bd706708c746 |
| Source note | uspto-grants-1993_10 |