HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylaniline → 3-Benzoylamino-2-hydroxy-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylaniline | HCID 949 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Methyl 3-amino-2-hydroxybenzoate | HCID 12782444 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Benzoylamino-2-hydroxy-benzoic acid methyl ester | HCID 19939920 | — |
Reaction Steps
20 mmol of methyl 3-amino-2-hydroxy-benzoate were stirred at room temperature in toluene with 20 mmol of benzoyl chloride for 4 hours with the addition of dimethylaniline, the mixture was concentrated and the residue was recrystallized from EtOH. M.p.: 105° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254692 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-91a8c18160b649148abbc175d2a3ffd6 |
| Source note | uspto-grants-1993_10 |