HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl acetoacetate → HCID 9867306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl acetoacetate | HCID 68329 | — |
| Reactant | (2Z)-3-Amino-2-butenenitrile | HCID 5325263 | — |
| Reactant | HCID 15676493 | HCID 15676493 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 9867306 | HCID 9867306 | 28% |
Reaction Steps
10 mmol of 2-phenyl-benzothiazole-7-carboxaldehyde, 10 mmol of isopropyl acetoacetate and 10 mmol of 3-aminocrotononitrile are boiled overnight in 20 ml of ethanol, the mixture is concentrated and the residue is purified on a silica gel column (cyclohexane/ethyl acetate=6:4) Yield: 28% of theory M.p.: 218° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254692 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-eab964e011ee42219dce04ab694de72d |
| Source note | uspto-grants-1993_10 |