Hydrochloric Acid → HCID 178469602, compound

Participants

Reaction Steps

5.62 g (13 mmol) of the compound (129) obtained above was added in a mixture solvent of 100 ml of chloroform and 100 ml of methanol, and 15 ml of 4N hydrochloric acid solution in dioxane was added to the solution. After stirring at room temperature for 30 minutes, the solvent was removed from the solution by distillation. Crystals obtained were dispersed in ethanol and filtrated. They were washed with ethanol and ether in this order to obtain 3.70 g of the subject compound (130) in a 90% yield.

Provenance & Evidence