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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 165679Generated: October 26, 2026

1,2-Dichloroethane → N1-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide

https://huagongshe.com/reaction/165679

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant2-(Phenylcarbamoyl)acetic acidHCID 256593—
Reactant(7-(4-Amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanoneHCID 59424653—
ProductN1-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamideHCID 45488051—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-97d1d0c38df341c7b10cc7a8f2cb2fe7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)