Sulfuric Acid → HCID 19788866, compound
Reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]([C:6]([F:10])([F:9])[CH2:7][CH3:8])=[CH:4][F:5].S(=O)(=O)(O)[OH:14]>O>[F:5][CH2:4][C:3]([OH:14])([C:6]([F:9])([F:10])[CH2:7][CH3:8])[C:2]([F:11])([F:12])[F:1]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
As another example, 2-fluoromethyl-1,1,1,3,3-pentafluoro-2-pentanol may be prepared by fluorinating 3-pentanone to form 3,3-difluoropentane which may then be dehydrogenated to form 3,3-difluoro-1-pentene. CF3 may then be reacted with the 3,3-difluoro-1-pentene to form 2-trifluoromethyl-1,3,3-trifluoropentane which may then be dehydrogenated to form 2-trifluoromethyl-1,3,3-trifluoro-1-pentene. The 2-trifluoromethyl-1,3,3-trifluoro-1-pentene may then be reacted with sulfuric acid and then water to form 2-fluoromethyl-1,1,1,3,3-pentafluoro-2-pentanol.
Sources & evidence
- ORD record
- ord-ff2c835492834ca0b2815c7c4d5e8c02
- Source dataset
- uspto-grants-1993_10
- Patent number
- US05254755
Reaction notes
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