Sulfuric Acid → 1,1,3,3-Tetrafluoro-2-methylpropan-2-ol
Reaction equation
[CH3:1][C:2]([CH:6]([F:8])[F:7])=[C:3]([F:5])[F:4].S(=O)(=O)(O)[OH:10]>O>[CH3:1][C:2]([OH:10])([CH:6]([F:8])[F:7])[CH:3]([F:5])[F:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
As another example, 2-methyl-1,1,3,3-tetrafluoro-2-propanol may be prepared by fluorinating commercially available 1,1-dichloro-2-propanone to form 1,1-difluoro-2-propanone which may then be reacted with CF2 carbene to form 2-methyl-1,1,3,3-tetrafluoro-1-propene. The 2-methyl-1,1,3,3-tetrafluoro-1-propene may then be reacted with sulfuric acid and then water to form 2-methyl-1,1,3,3-tetrafluoro-2-propanol.
Sources & evidence
- ORD record
- ord-53b1db575a3d42f9bcfb340c59adbaf6
- Source dataset
- uspto-grants-1993_10
- Patent number
- US05254755
Reaction notes
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