Sulfuric Acid → HCID 19788871, compound

HRID 1656842Notes

Reaction equation

HRID 1656842 reaction equation
[F:1][CH2:2][C:3]([CH2:7][F:8])=[C:4]([F:6])[F:5].S(=O)(=O)(O)[OH:10]>O>[F:1][CH2:2][C:3]([OH:10])([CH2:7][F:8])[CH:4]([F:6])[F:5]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 19788900HCID 19788900, compound

Product 1

HCID 19788871HCID 19788871, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

As another example, the 2-fluoromethyl-1,1,3-trifluoro-2-propanol may be prepared by oxidizing commercially available 1,3-difluoro-2-propanol to 1,3-difluoro-2-propanone which may then be reacted with a CF2 carbene to form 2-fluoromethyl-1,1,3-trifluoro-1-propene. The 2-fluoromethyl-1,1,3-trifluoro-1-propene may then be reacted with sulfuric acid and then water to form 2-fluoromethyl-1,1,3-trifluoro-2-propanol.

Sources & evidence

ORD record
ord-48566edee5684719985f862890931825
Source dataset
uspto-grants-1993_10
Patent number
US05254755

Reaction notes

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