Sodium Hydroxide → HCID 13520598, compound

Participants

Reaction Steps

A solution of 3.88 g of 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-5-formylindole in 40 ml of THF is added dropwise, under N2 and with stirring, to a suspension of 0.57 g of lithium aluminum hydride in 20 ml of THF. The mixture is stirred for a further hour at 20° and is decomposed with dilute sodium hydroxide solution and then with water and is filtered and worked up in the customary manner to give 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-5-hydroxymethylindole, m.p. 178°.

Provenance & Evidence