Ammonia → HCID 13520603, compound

Participants

Reaction Steps

0.02 mol of concentrated ammonia (D=0.9) is added dropwise at 20° to a solution of 4.18 g of methyl 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-indole-5-carboxylate in 30 ml of dimethylformamide. The mixture is stirred for a further hour at 20° and worked up in the customary manner to give 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-indole-5-carboxamide, m.p. 207°-208°.

Provenance & Evidence