Trimethyl orthoformate → HCID 19598016, compound

HRID 1657045Notes

Reaction equation

HRID 1657045 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1C=O.[CH:13]([O:18][CH3:19])([O:16][CH3:17])OC>CO>[OH:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:13]([O:16][CH3:17])[O:18][CH3:19]

Participants

4

Reactant 2

HCID 9005Trimethyl orthoformateHCID 668085-Nitrosalicylaldehyde

Product 1

HCID 19598016HCID 19598016, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-Hydroxy-5-nitrobenzaldehyde (3.34 g) was dissolved in methanol (30 ml). Trimethyl orthoformate (20 ml) and then Dowex 50W×8 (H+ form)(generally 2 ml) were added to this solution. The mixture was stirred for 30 min. at room temperature. The resin was removed from the reaction mixture by passing the mixture through an alumina. The filtrate was evaporated to give the title compound (4.0 g) having the following physical data.

Workup

  1. customThe resin was removed from the reaction mixture
  2. customThe filtrate was evaporated

Sources & evidence

ORD record
ord-2f1c863af8514322b5abfb5bea8ea1c8
Source dataset
uspto-grants-1993_10
Patent number
US05256686

Reaction notes

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