反应详情

A mixture of 24.99 (0.10 mole) dibutyltin oxide, 21.6g (0.20 mole) 3-mercapto-1,2-propanediol and 300 ml toluene were charged to a round-bottom glass reaction flask fitted with a mechanical stirrer, thermocouple and a reflux condenser with a Dean-Stark water trap. The mixture was heated to reflux temperature, with agitation, and continued at reflux until a clear homogeneous solution formed and all water of reaction was collected in the trap. Removal of the toluene (flash evaporator) yielded 44.5g (99.5% yield) of dibutyltin-bis-(2,3-dihydroxypropylmercaptide), a straw-colored viscous liquid.

1. additionwere charged to a round-bottom glass reaction flask
2. customfitted with a mechanical stirrer
3. temperatureThe mixture was heated
4. temperatureto reflux temperature
5. temperatureat reflux until a clear homogeneous solution
6. customformed
7. customwas collected in the trap
8. customRemoval of the toluene (flash evaporator)