4-Cyanobenzoyl chloride → HCID 20083620, compound

HRID 1657245Notes

Reaction equation

HRID 1657245 reaction equation
S(O)(O)(=O)=O.[CH3:6][O:7][C:8](=[O:20])[CH2:9][NH:10][C:11]1[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][NH2:19])=[CH:13][CH:12]=1.[C:21]([C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=1)#[N:22]>C1(C)C=CC=CC=1>[CH3:6][O:7][C:8](=[O:20])[CH2:9][NH:10][C:11]1[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][NH:19][C:27](=[O:28])[C:26]2[CH:30]=[CH:31][C:23]([C:21]#[N:22])=[CH:24][CH:25]=2)=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 801724-Cyanobenzoyl chlorideHCID 70055170HCID 70055170, compound

Product 1

HCID 20083620HCID 20083620, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

920 mg of N-[p-(2-aminoethyl)phenyl]glycine methyl ester sulphate were reacted in analogy to Example 3 with 4-cyanobenzoyl chloride to give N-[p-[2-(p-cyanobenzamido) ethyl]phenyl]glycine methyl ester, melting point 161°-162° C. (from toluene).

Sources & evidence

ORD record
ord-28ecc079de6743229478e96b6c44b186
Source dataset
uspto-grants-1993_10
Patent number
US05256812

Reaction notes

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