Sodium borohydride → HCID 68129170, compound

Participants

Reaction Steps

5.2 g. of the methyl ester of 20-cyano-3-oxo-1,4,17(20)-pregnatriene-21-oic acid is reacted, under the conditions indicated in Example 9(b), in 150 ml. of methanol at 0° C. with 200 mg. of sodium borohydride. After a reaction time of 7 hours, the reaction mixture is worked up as described in Example 9(b), and after recrystallization from methanol, 4.92 g. of the methyl ester of 20-cyano-3-oxo-1,4-pregnadiene-21-oic acid is produced, m.p. 208°-210° C.

Provenance & Evidence