Acetonitrile → HCID 131710252, compound

Participants

Reaction Steps

The base from part (b) and 1.3 g. of maleic acid are dissolved in 25 ml. of warm MeCN and diluted to approximately 600 ml. with ether. On rubbing and standing in the cold, the crystalline maleate salt slowly separates. After four days in the cold, the maleate salt is filtered, washed with ether, and dried in vacuo yielding 4.1 g. (32%); m.p. 109°-111°. Crystallization from 25 ml. methanol-250 ml. ether yields 3.5 g. (27%) of nearly colorless 3a,4,5,6,7,8-hexahydro-N,N-dimethyl-3-phenyl-8-(phenylmethylene)-cyclohepta[c]pyrazole-2(3H)-propanamine, maleate, m.p. 109°-111°.

Provenance & Evidence