Dimethylamine → Dimethylamino-3-(phenylmethyl)-1,2,4-oxadiazole
Reaction equation
[C:1]1([CH2:7][C:8]2[N:12]=[C:11](C(Cl)(Cl)Cl)[O:10][N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][NH:18][CH3:19]>>[CH3:17][N:18]([CH3:19])[C:11]1[O:10][N:9]=[C:8]([CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[N:12]=1Participants
3
Procedure
3-(Phenylmethyl)-5-(trichloromethyl)-1,2,4-oxadiazole is reacted with dimethylamine to yield 5-(dimethylamino)-3-(phenylmethyl)-1,2,4-oxadiazole.
Sources & evidence
- ORD record
- ord-197c004f4a3849489c7ffbc51c60443a
- Source dataset
- uspto-grants-1976_06
- Patent number
- US03960849
Reaction notes
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