Acetic Acid → HCID 54533504, compound

HRID 1657472Notes

Reaction equation

HRID 1657472 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:12]=O)[C:6](=[CH:10][CH:11]=1)[C:7]([OH:9])=[O:8].[S:14]1[CH2:20][C:18](=[O:19])[NH:17][C:15]1=[S:16].C(O)(=O)C.C([O-])(=O)C.[Na+]>O>[C:7]([C:6]1[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][C:5]=1[CH:12]=[C:20]1[S:14][C:15](=[S:16])[NH:17][C:18]1=[O:19])([OH:9])=[O:8]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 1201546RhodanineHCID 162152102-Formyl-4-methoxybenzoic acid

Product 1

HCID 54533504HCID 54533504, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred hot solution of 4.23 g. (23.5 mM) of 4-methoxyphthalaldehydic acid and 3.13 g. (23.5 mM) of rhodanine in 16.5 ml. of acetic acid is added 6.33 g. (77.2 mM) of anhydrous sodium acetate. The resulting hot solution is refluxed for 0.5 hour, whereupon a solid yellow mass forms. The mixture is cooled, poured into water, to yield 5-(2-carboxy-5-methoxybenzylidene) rhodanine.

Workup

  1. temperatureThe resulting hot solution is refluxed for 0.5 hour, whereupon a solid yellow mass forms
  2. temperatureThe mixture is cooled

Sources & evidence

ORD record
ord-1ef4b414c8974f5da2a0d27459a12d30
Source dataset
uspto-grants-1976_06
Patent number
US03960892

Reaction notes

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