HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 8-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-(2-Carboxy-3-methoxybenzylidene)rhodanine | HCID 54306741 | — |
| Product | 8-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylic acid | HCID 21440750 | — |
Reaction Steps
A solution of the benzylidenerhodanine of Example 10 in 46 ml. of 15% NaOH is refluxed for 0.75 hour, cooled, and poured into dilute HCl. The resulting tan precipitate is collected and air-dried. Two recrystallizations from methanol (charcoal) give 8-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylic acid as a pale yellow solid, m.p. 275° (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03960892 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-53f3d0244d5d4b08a6e26f6828b8769e |
| Source note | uspto-grants-1976_06 |