Acetic Acid → HCID 54339098, compound

HRID 1657484Notes

Reaction equation

HRID 1657484 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]([C:6]([OH:8])=[O:7])[C:4]=1[CH:12]=O.[S:14]1[CH2:20][C:18](=[O:19])[NH:17][C:15]1=[S:16].C(O)(=O)C.C([O-])(=O)C.[Na+]>O>[C:6]([C:5]1[CH:9]=[CH:10][CH:11]=[C:3]([O:2][CH3:1])[C:4]=1[CH:12]=[C:20]1[S:14][C:15](=[S:16])[NH:17][C:18]1=[O:19])([OH:8])=[O:7]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 1201546RhodanineHCID 127303562-Formyl-3-methoxybenzoic acid

Product 1

HCID 54339098HCID 54339098, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred hot solution of 0.45 g. (2.50 mM) of 3-methoxyphthalaldehydic acid and 0.34 g. (2.50 mM) rhodanine in 3ml. of acetic acid is added 0.68 g. (8.2 mM) of anhydrous sodium acetate. The resulting solution is refluxed 1.5 hours, cooled, and poured into 40 ml. of water to give a yellow gum which slowly solidifies to a yellow solid. The solid is collected, washed with water, and air-dried to give 5-(2-carboxy-6-methoxybenzylidene)rhodanine.

Workup

  1. temperatureThe resulting solution is refluxed 1.5 hours
  2. temperaturecooled
  3. additionpoured into 40 ml
  4. customThe solid is collected
  5. washwashed with water
  6. customair-dried

Sources & evidence

ORD record
ord-b47b0384f5634c49ac3e014a1397a100
Source dataset
uspto-grants-1976_06
Patent number
US03960892

Reaction notes

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