Sodium Azide → HCID 178514616, compound

Participants

Reaction Steps

A mixture of 4.22 g. of trans 4-(p-fluorophenyl)cyclohexanol methanesulfonate (obtained as in Example 17) and an equal weight of sodium azide in 45 ml. of dimethylformamide is heated at about 95° C. for about 12 hours. The mixture is taken to dryness on a rotary evaporator and the residue dissolved in water and benzene. The organic layer is washed with water and brine to yield cis 4-(p-fluorophenyl)cyclohexan-1-ylazide.

Provenance & Evidence