Propargyl alcohol → HCID 21534973, compound

Participants

Reaction Steps

9-(N-Methylcarbamoyloxy)xanthene (3.0 g., 11.8 mmoles.) was stirred with 18 ml. of propargyl alcohol for 1.5 hours at room temperature, and the mixture was then filtered. The filtrate was evaporated in vacuo, and the residue was dissolved in ice-cold ether and washed twice with 20 ml. of ice-cold 10% aqueous acetic acid, 15 ml. of ice-cold water, and 10 ml. of ice-cold 5% aqueous sodium bicarbonate solution. After drying over potassium carbonate, the solvent was removed in vacuo. The resulting solid was recrystallized from hexane to give propargyl 9-xanthenyl ether, m.p. 74°-76°C.

Provenance & Evidence