Dicyclohexylcarbodiimide → 1,2-Dihydro-5,5-dimethyl-8-(3-methyl-2-octyl)-10-[4-(morpholino)butyryloxy]-3H,5H-thiopyrano[2,3-c][1]benzopyran hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	Dicyclohexylcarbodiimide	HCID 10868	—
Reactant	8-(1,2-Dimethylheptyl)-1,2,3,5-tetrahydro-5,5-dimethylthiopyrano(2,3-c)(1)benzopyran-10-ol	HCID 65443	—
Reactant	4-Morpholin-4-Yl-Butyric Acid Hydrochloride	HCID 12733746	—
Product	1,2-Dihydro-5,5-dimethyl-8-(3-methyl-2-octyl)-10-[4-(morpholino)butyryloxy]-3H,5H-thiopyrano[2,3-c][1]benzopyran hydrochloride	HCID 21433913	—

Reaction Steps

The benzopyran of Example 25 is reacted with γ-morpholinobutyric acid, hydrochloride salt and dicyclohexylcarbodiimide according to the method of Example 10 to yield the desired ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US03960871
Source dataset	uspto-grants-1976_06
ORD ID	ord-7a4a428fdc654819bb57433231dd26e7
Source note	uspto-grants-1976_06