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HRID1657658

反应详情

EQUATION

反应方程式

HRID 1657658 的结构方程式

REACTANTS

反应物

3
结构：C(=NC1CCCCC1)=NC1CCCCC1
HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CC(C)S1
HCID3043883

2,4,4-Trimethyl-7-(3-methyloctan-2-yl)-1,4-dihydro-2H-thieno[2,3-c][1]benzopyran-9-ol

C23H34O2S

结构：Cl.O=C(O)CCCN1CCOCC1
HCID12733746

4-(Morpholin-4-yl)butanoic acid--hydrogen chloride (1/1)

C8H16ClNO3

PRODUCTS

生成物

1
结构：CCCCCC(C)C(C)c1cc(OC(=O)CCCN2CCOCC2)c2c(c1)OC(C)(C)C1=C2CC(C)S1.Cl
HCID21520000

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

1,2-Dihydro-2,4,4-trimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno-[2,3-c][1]benzopyran, dicyclohexylcarbodiimide and γ-morpholinobutyric acid hydrochloride are combined in methylene chloride and stirred at room temperature. The insoluble dicyclohexylurea is removed by filtration and the methylene chloride is removed on a rotary evaporator. The residue is crystallized from ether to give 1,2-dihydro-2,4,4-trimethyl-9-[4-(morpholino)butyryloxy]-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran hydrochloride.

WORKUP

后处理

  1. customThe insoluble dicyclohexylurea is removed by filtration
  2. customthe methylene chloride is removed on a rotary evaporator
  3. customThe residue is crystallized from ether