HRID1657660

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CC(C)(C)S1

HCID3043882

2,2,4,4-Tetramethyl-7-(3-methyloctan-2-yl)-1,4-dihydro-2H-thieno[2,3-c][1]benzopyran-9-ol

C24H36O2S

HCID68132093

未命名化合物

PRODUCTS

生成物

结构：Br.CCCCCC(C)C(C)c1cc(OC(=O)CCCN2CCCC2)c2c(c1)OC(C)(C)C1=C2CC(C)(C)S1

HCID21533417

未命名化合物

PROCEDURE

实验过程

By reacting 1,2-dihydro-9-hydroxy-7-(3-methyl-2-octyl)-2,2,4,4-tetramethyl-4H-thieno-[2,3-c][1]benzopyran with γ-pyrrolidinobutyric acid hydrobromide salt and dicyclohexylcarbodiimide according to the method of Example 10 there is obtained 1,2-dihydro-7-(3-methyl-2-octyl)-9-[4-(pyrrolidino)butyryloxy]-2,2,4,4-tetramethyl-4H-thieno-[2,3-c][1]benzopyran hydrobromide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-50ee72fa119c48909fd68c471e3be1b1
来源数据集: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US03960871
来源说明: uspto-grants-1976_06

反应 SMILES

[OH:1][C:2]1[C:7]2[C:8]3[CH2:16][C:15]([CH3:18])([CH3:17])[S:14][C:9]=3[C:10]([CH3:13])([CH3:12])[O:11][C:6]=2[CH:5]=[C:4]([CH:19]([CH:21]([CH3:27])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH3:20])[CH:3]=1.[BrH:28].[N:29]1([CH2:34][CH2:35][CH2:36][C:37](O)=[O:38])[CH2:33][CH2:32][CH2:31][CH2:30]1.C1(N=C=NC2CCCCC2)CCCCC1>>[BrH:28].[CH3:27][CH:21]([CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH:19]([C:4]1[CH:3]=[C:2]([O:1][C:37](=[O:38])[CH2:36][CH2:35][CH2:34][N:29]2[CH2:33][CH2:32][CH2:31][CH2:30]2)[C:7]2[C:8]3[CH2:16][C:15]([CH3:17])([CH3:18])[S:14][C:9]=3[C:10]([CH3:12])([CH3:13])[O:11][C:6]=2[CH:5]=1)[CH3:20]