HCID 21529597, compound → HCID 21529593, compound

HRID 1657679Notes

Reaction equation

HRID 1657679 reaction equation
[CH3:1][CH:2]1[C:7]2([CH2:11][CH2:10][CH2:9][CH2:8]2)[C:6](=[O:12])[CH2:5][CH2:4][CH2:3]1.[CH3:13][Mg]I>>[CH3:13][C:6]1([OH:12])[CH2:5][CH2:4][CH2:3][CH:2]([CH3:1])[C:7]21[CH2:11][CH2:10][CH2:9][CH2:8]2

Participants

3

Reactant 2

HCID 21529597HCID 21529597, compoundHCID 178418373HCID 178418373, compound

Product 1

HCID 21529593HCID 21529593, compoundYield 82%

Procedure

10-methyl-spiro[4.5]decan-6-one was alkylated by means of methyl-magnesium iodide under the reaction conditions commonly used in a Grignard reaction. 6,10-dimethyl-spiro[4.5]-decan-6-ol was thus obtained with an yield of 82 %.

Workup

  1. customcommonly used in a Grignard reaction

Sources & evidence

ORD record
ord-ff45c26332964745b5b2de14e97800a5
Source dataset
uspto-grants-1976_06
Patent number
US03962147

Reaction notes

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