Sodium Carbonate → L-Phenylalanine, methyl ester

Participants

Reaction Steps

241 g (1.1 Mole) L-phenylalanine methyl ester hydrochloride was dissolved in 900 ml water, and the solution was neutralized with 71 g sodium carbonate. The liberated L-phenylalanine methyl ester was extracted with 2 l ethylene dichloride to give an L-phenylalanine methyl ester solution containing 1.05 mole of the ester. 150 ml Methanol was added to the solution.

Provenance & Evidence