3-Hydrazinyl-N,N-dimethyl-1-propanamine → HCID 53921981, compound

HRID 1657692Notes

Reaction equation

HRID 1657692 reaction equation
[C:1]1([CH:7]=[C:8]2[C:13](=O)[C:12](=[CH:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:11][S:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:22][N:23]([CH3:29])[CH2:24][CH2:25][CH2:26][NH:27][NH2:28]>CO>[CH3:22][N:23]([CH3:29])[CH2:24][CH2:25][CH2:26][N:27]1[CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:8]2[CH2:9][S:10][CH2:11][C:12](=[CH:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:13]2=[N:28]1

Participants

4

Reactant 2

HCID 1204233-Hydrazinyl-N,N-dimethyl-1-propanamineHCID 336779tetrahydro-3,5-bis(phenylmethylene)-4H-thiopyran-4-one

Product 1

HCID 53921981HCID 53921981, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Tetrahydro-3,5-bis-(phenylmethylene)-4H-thiopyran-4-one (5g) is refluxed with 2.1g of 3-dimethylaminopropylhydrazine in 50ml of methanol for 4 hours. The solvent is evaporated off and the residue is crystallized from 30ml of acetonitrile to yield 3.9g of the title compound, melting point 83°-85°C.

Workup

  1. customThe solvent is evaporated off
  2. customthe residue is crystallized from 30ml of acetonitrile

Sources & evidence

ORD record
ord-7f2e1e94eb4a467eae75aab2063d6861
Source dataset
uspto-grants-1976_06
Patent number
US03962222

Reaction notes

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