HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetyl chloride → p-Nitrobenzyl 7-phenylacetamido-3-chloro-3-cephem-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetyl chloride | HCID 7679 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 4-Nitrobenzyl 7-amino-3-chloro-3-cephem-4-carboxylate | HCID 67643556 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | p-Nitrobenzyl 7-phenylacetamido-3-chloro-3-cephem-4-carboxylate | HCID 67655773 | — |
Reaction Steps
For example, p-nitrobenzyl 7-amino-3-chloro-3-cephem-4-carboxylate is reacted with phenylacetyl chloride in cold aqueous acetone containing sodium bicarbonate to provide p-nitrobenzyl 7-phenylacetamido-3-chloro-3-cephem-4-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03962227 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-9b8d53a350fe4f6e91477a4095ff0930 |
| Source note | uspto-grants-1976_06 |