Phenoxyacetyl chloride → HCID 70562397, compound

HRID 1657727Notes

Reaction equation

HRID 1657727 reaction equation
[NH2:1][CH:2]1[C:26](=[O:27])[N:4]2[C:5]([C:10]([O:12][CH:13]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:11])=[C:6]([Br:9])[CH2:7][S:8][C@H:3]12.[O:28]([CH2:35][C:36](Cl)=[O:37])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>N1C=CC=CC=1>[O:28]([CH2:35][C:36]([NH:1][CH:2]1[C:26](=[O:27])[N:4]2[C:5]([C:10]([O:12][CH:13]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:11])=[C:6]([Br:9])[CH2:7][S:8][C@H:3]12)=[O:37])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1

Participants

4

Reactant 2

HCID 69703Phenoxyacetyl chlorideHCID 68852455HCID 68852455, compound

Product 1

HCID 70562397HCID 70562397, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Diphenylmethyl 7-amino-3-bromo-3-cephem-4-carboxylate is reacted with phenoxyacetyl chloride in the presence of pyridine to provide diphenylmethyl 7-phenoxyacetamido-3-bromo-3-cephem-4-carboxylate.

Sources & evidence

ORD record
ord-43acc3b9e8a242e4b83c84819a3af9c0
Source dataset
uspto-grants-1976_06
Patent number
US03962227

Reaction notes

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