2-Methylfuran-3-carbonyl chloride → trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(2-methyl-3-furoyl)piperazine hydrochloride

HRID 1657776Notes

Reaction equation

HRID 1657776 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][C@@H:14]([CH3:16])[NH:13][CH2:12][C@@H:11]2[CH3:17])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:18][C:19]1[O:20][CH:21]=[CH:22][C:23]=1[C:24]([Cl:26])=[O:25]>C1C=CC=CC=1>[ClH:26].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][C@@H:14]([CH3:16])[N:13]([C:24]([C:23]3[CH:22]=[CH:21][O:20][C:19]=3[CH3:18])=[O:25])[CH2:12][C@@H:11]2[CH3:17])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 27598502-Methylfuran-3-carbonyl chlorideHCID 44361659trans-1-(3-Phenylpropyl)-2,5-dimethylpiperazine

Product 1

HCID 68131035trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(2-methyl-3-furoyl)piperazine hydrochloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

The compound was obtained by following the same process as in Example 2 from a mixture of trans-1-(3-phenylpropyl)-2,5-dimethylpiperazine, 2-methyl-3-furoyl chloride and benzene.

Workup

  1. customThe compound was obtained

Sources & evidence

ORD record
ord-d952a127ff7742c9bc85d1deb5deb05f
Source dataset
uspto-grants-1976_06
Patent number
US03962249

Reaction notes

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