HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → 2-Chloro-10-(1-pyrrolin-2-YL)phenoxazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-Chlorophenoxazine | HCID 10632580 | — |
| Product | 2-Chloro-10-(1-pyrrolin-2-YL)phenoxazine | HCID 22754317 | — |
Reaction Steps
Reaction of 2-chlorophenoxazine, 2-pyrrolidinone, and phosphorus oxychloride according to the procedure of Example 1 provides the free base 2-CHLORO-10-(1-PYRROLIN-2-YL)PHENOXAZINE as a distillable oil, b.p. 150°-165°C. at 0.1 mm Hg. Conversion of the free base to the hydrochloride salt affords 2-CHLORO-10-(1-PYRROLIN-2-YL)-PHENOXAZINE HYDROCHLORIDE, m.p. 209.5°-213.5°C. (corr.), in a 40% overall yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03962252 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-55b16e14ff8c426b81edfaef7bd4eef0 |
| Source note | uspto-grants-1976_06 |