Methyl Isocyanate → HCID 21530339, compound

HRID 1657801Notes

Reaction equation

HRID 1657801 reaction equation
[CH3:1][N:2]1[C:8]([CH3:10])([CH3:9])[CH2:7][C:6](=[O:11])[NH:5][CH2:4][C:3]1([CH3:13])[CH3:12].[CH3:14][N:15]=[C:16]=[O:17]>>[CH3:14][NH:15][C:16]([N:5]1[C:6](=[O:11])[CH2:7][C:8]([CH3:9])([CH3:10])[N:2]([CH3:1])[C:3]([CH3:13])([CH3:12])[CH2:4]1)=[O:17]

Participants

3

Reactant 2

HCID 12228Methyl IsocyanateHCID 53759496HCID 53759496, compound

Product 1

HCID 21530339HCID 21530339, compound

Procedure

Using the same conditions as in Example 4, 2.76 parts of 1,2,2,7,7 -pentamethyl-1,4-diazacycloheptan-5-one and 0.93 parts of methyl isocyanate afforded a colourless solid which was crystallised from petroleum ether (of boiling range 60°-80°C) to give 4-methylcarbamoyl-1,2,2,7,7-pentamethyl-1,4-diazacycloheptan-5-one. This material had a melting point of 111°-113°C and gave the following elemental analysis by weight:

Workup

  1. customafforded a colourless solid which
  2. customwas crystallised from petroleum ether (of boiling range 60°-80°C)

Sources & evidence

ORD record
ord-5821a54e0caf45469e6e10740b1ff22e
Source dataset
uspto-grants-1976_06
Patent number
US03962255

Reaction notes

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