4-Methylphenyl isocyanate → 4-p-Tolylcarbamoyl-2,2,7,7-tetramethyl-1,4-diazacycloheptan-5-one

HRID 1657809Notes

Reaction equation

HRID 1657809 reaction equation
[CH3:1][C:2]1([CH3:12])[CH2:8][NH:7][C:6](=[O:9])[CH2:5][C:4]([CH3:11])([CH3:10])[NH:3]1.[C:13]1([CH3:22])[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1>>[C:13]1([CH3:22])[CH:18]=[CH:17][C:16]([NH:19][C:20]([N:7]2[C:6](=[O:9])[CH2:5][C:4]([CH3:11])([CH3:10])[NH:3][C:2]([CH3:12])([CH3:1])[CH2:8]2)=[O:21])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 693254-Methylphenyl isocyanateHCID 5469102,2,7,7-Tetramethyl-1,4-diazepan-5-one

Product 1

HCID 215302984-p-Tolylcarbamoyl-2,2,7,7-tetramethyl-1,4-diazacycloheptan-5-one

Procedure

Using the same procedure as described in Example 4, 17 parts of 2,2,7,7-tetramethyl-1,4-diazacycloheptan-5-one and 14.3 parts of p-tolyl isocyanate were reacted together and afforded a solid material which was recrystallised from petroleum ether (of boiling range 60° to 80°C) to yield 21 parts of 4-p-tolylcarbamoyl-2,2,7,7-tetramethyl-1,4-diazacycloheptan-5-one of melting point 126°C. This material gave the following elemental analysis by weight:

Workup

  1. customwere reacted together
  2. customafforded a solid material which
  3. customwas recrystallised from petroleum ether (of boiling range 60° to 80°C)

Sources & evidence

ORD record
ord-460147e67be84911ad9f86ceb4751479
Source dataset
uspto-grants-1976_06
Patent number
US03962255

Reaction notes

Loading…