化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 1,3-Dihydro5-fluoro-1'-methylspiro[isobenzofuran-1,4'-piperidine]
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 4-(5-Fluoro-alpha-hydroxy-2-tolyl)-4-hydroxy-1-methylpiperidine | HCID 86733529 | — |
| 生成物 | 1,3-Dihydro5-fluoro-1'-methylspiro[isobenzofuran-1,4'-piperidine] | HCID 21506822 | — |
反応手順
Treatment of 4-(5-fluoro-α-hydroxy-2-tolyl)-4-hydroxy-1-methylpiperidine with hydrochloric acid by the method described in Example 16d provides 1,3-dihydro-5-fluoro-1'-methylspiro[isobenzofuran-1,4'-piperidine].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03962259 |
| 出典データセット | uspto-grants-1976_06 |
| ORD ID | ord-bf2ffb0213894c20826bd72cd39a2d33 |
| 出典メモ | uspto-grants-1976_06 |