HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzhydryl 2-chloroethyl ether → 1'-(2-Benzhydryloxyethyl)-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzhydryl 2-chloroethyl ether | HCID 141724 | — |
| Reactant | 3H-spiro(isobenzofuran-1,4'-piperidin)-3-one | HCID 9834255 | — |
| Product | 1'-(2-Benzhydryloxyethyl)-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]-3-one | HCID 21506827 | — |
Reaction Steps
Reaction of 1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]-3-one and 2-benzhydryloxy-1-chloroethane by the method described in Example 5d provides 1'-(2-benzhydryloxyethyl)-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]-3-one as colorless crystals, m.p. 99°-100°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03962259 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-b330dd256418466d98e3f72ece7461e5 |
| Source note | uspto-grants-1976_06 |