Sulfuric Acid → HCID 21531595, compound

HRID 1657921Notes

Reaction equation

HRID 1657921 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]([CH3:14])([CH3:13])[CH3:12].[Cl:15][CH2:16]OC.S(=O)(=O)(O)O>>[Br:1][C:2]1[C:3]([C:11]([CH3:14])([CH3:13])[CH3:12])=[C:4]([CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1)[CH2:16][Cl:15]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 7864Chloromethyl Methyl EtherHCID 2385872-Bromo-1-tert-butyl-4-nitrobenzene

Product 1

HCID 21531595HCID 21531595, compound

Procedure

A mixture of 30 parts of 2-bromo-1-tert-butyl-4-nitrobenzene and 30 parts of chloromethylmethyl ether is stirred vigorously while adding dropwise 20 parts of 60% fuming sulfuric acid. The resultant mixture is allowed to stand until the apparent reaction ceases and is then poured into ice water. The solid is removed by filtration and washed with water to give 3-bromo-2-tert-butyl-5-nitrobenzyl chloride.

Workup

  1. customto stand until the apparent reaction ceases
  2. customThe solid is removed by filtration
  3. washwashed with water

Sources & evidence

ORD record
ord-571a3836874448909db47330f5f9ff07
Source dataset
uspto-grants-1976_06
Patent number
US03962307

Reaction notes

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