Water → HCID 178420823, compound

HRID 1657934Notes

Reaction equation

HRID 1657934 reaction equation
[PH:1]([O:4][PH:5]([OH:7])=[O:6])([OH:3])=[O:2].[O:8]1[CH:10]=[CH:9]1.O.O1CCOCC1>CC(C)=O>[PH:1]([O:4][PH:5]([OH:7])=[O:6])([OH:3])=[O:2].[O:8]1[CH2:10][CH2:9]1

Participants

5

Reactant 3

HCID 962Water4×HCID 312751,4-DioxaneHCID 178420822HCID 178420822, compound

Product 1

HCID 178420823HCID 178420823, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The hydrolysis of epoxy ethane diphosphonate to produce the dihydroxy ethane diphosphonate proceeds according to the following general reaction: ##EQU6## wherein R3 is the same as defined above. The aforementioned reaction may be carried out by mixing the epoxy ethene diphosphonate in a sufficient volume of water, i.e., at least stoichiometric quantities, preferably a molar ratio of water to EEDP of 1:1 to 20:1, and heating the resultant mass until substantially complete hydrolysis occurs. The use of greater than stoichiometric quantities of water functions as a diluent for the reaction system. It is also found that substantially water-miscible organic diluents which have a boiling point between about 50°C and 150°C, preferably from about 70°C to about 100°C, such as dioxane, acetone, lower alcohols (e.g., methanol, ethanol, propanol and butanol) are suitable as a reaction medium or diluent in which the above-described hydrolysis reaction can be conducted.

Workup

  1. customproceeds according to the following general reaction
  2. customThe aforementioned reaction
  3. customuntil substantially complete hydrolysis
  4. custompreferably from about 70°C to about 100°C
  5. customthe above-described hydrolysis reaction

Sources & evidence

ORD record
ord-f71e92cf31e9437b97e63e4395472f26
Source dataset
uspto-grants-1976_06
Patent number
US03962318

Reaction notes

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