Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Fluorosulfuric acid, ethyl ester | HCID 67791 | — |
| Reactant | Trifluoromethylmalonyl fluoride | HCID 12951306 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 21532248 | HCID 21532248 | 81.7% |
Reaction Steps
A solution of 9.2 g (0.09 mol) of triethylamine in 25 ml of ether was added dropwise to a stirred solution of 17.6 g (0.10 mol) of trifluoromethylmalonyl fluoride in 50 ml of ether at -80°C. To the resulting suspension of solid was added 14.1 g (0.11 mol) of ethyl fluorosulfate and the mixture was then allowed to warm to 25°C with stirring. The homogeneous reaction mixture developed two layers after standing overnight. Distillation gave 15 g (74%) of ethyltrifluoromethylmalonyl fluoride, bp 54°-56°C (260 mm), identified by ir.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03962325 |
|---|
| Source dataset | uspto-grants-1976_06 |
|---|
| ORD ID | ord-8ee4667c0e43459d922af0738f2f1c98 |
|---|
| Source note | uspto-grants-1976_06 |
|---|
