HRID1658009

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21529910

未命名化合物

PRODUCTS

生成物

结构：COCC1=C(C(=O)[O-])N2C(=O)[C@](N=[N+]=[N-])(OC)[C@H]2SC1

HCID131710321

未命名化合物

结构：CO[C@@]1(N=[N+]=[N-])C(=O)N2C(C(=O)[O-])=C(COC(=O)C(C)C)CS[C@@H]21

HCID131710323

未命名化合物

PROCEDURE

实验过程

Following the procedures described in Example 40 p-methoxybenzyl 5-methoxymethyl-6H-1,3-thiazine-4-carboxylate, 2,2,2-trichloroethyl 5-methyl-6H-1,3-thiazine-4-carboxylate or methoxymethyl 5-isobutyryloxymethyl-6H-1,3-thiazine-4-carboxylate are reacted with 2-azido-2-methoxyacetyl chloride to obtain p-methoxybenzyl dl-3-methoxymethyl-7β-azido-7α-methoxy-3-cephem-4-carboxylate, 2,2,2-trichloroethyl d1-3-methyl-7β-azido-7α-methoxy-3-cephem-4-carboxylate and methoxymethyl dl-3-isobutyryloxymethyl-7β-azido-7α-methoxy-3-cephem-4-carboxylate, respectively.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1161f07cb61348bf98c76edc3f0fd7f7
来源数据集: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US03962224
来源说明: uspto-grants-1976_06

反应 SMILES

[CH3:1][O:2][CH2:3][C:4]1[CH2:9][S:8][CH:7]=[N:6][C:5]=1[C:10]([O:12]CC1C=CC(OC)=CC=1)=[O:11].CC1CSC=NC=1C(OCC(Cl)(Cl)Cl)=O.[C:37]([O:42][CH2:43][C:44]1[CH2:49][S:48][CH:47]=[N:46][C:45]=1[C:50]([O:52]COC)=[O:51])(=[O:41])[CH:38]([CH3:40])[CH3:39].[N:56]([CH:59]([O:63][CH3:64])[C:60](Cl)=[O:61])=[N+:57]=[N-:58]>>[CH3:1][O:2][CH2:3][C:4]1[CH2:9][S:8][C@@H:7]2[C@@:59]([N:56]=[N+:57]=[N-:58])([O:63][CH3:64])[C:60](=[O:61])[N:6]2[C:5]=1[C:10]([O-:12])=[O:11].[C:37]([O:42][CH2:43][C:44]1[CH2:49][S:48][C@@H:47]2[C@@:59]([N:56]=[N+:57]=[N-:58])([O:63][CH3:64])[C:60](=[O:61])[N:46]2[C:45]=1[C:50]([O-:52])=[O:51])(=[O:41])[CH:38]([CH3:39])[CH3:40]