Ethanol → HCID 54680399, compound

HRID 1658093Notes

Reaction equation

HRID 1658093 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:13])=[CH:7][C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1.[N+:14]([O-])([OH:16])=[O:15].C(O)C>C(O)(=O)C>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:13])=[C:7]([N+:14]([O-:16])=[O:15])[C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 944Nitric AcidHCID 54677681HCID 54677681, compound

Product 1

HCID 54680399HCID 54680399, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A suspension of 7-chloro-4-hydroxycarbostyril (0.5g.) in glacial acetic acid (4 ml.) was nitrated with concentrated nitric acid (0.7ml.) at 100°C and worked up in the usual manner to give the title compound, m.p. (aqueous ethanol) 166°-167°C.

Sources & evidence

ORD record
ord-20c9a0ee8ad74440bfe6491ad7d3c525
Source dataset
uspto-grants-1976_06
Patent number
US03962445

Reaction notes

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