Ethanol → 4-Hydroxy-N-methylcarbostyril

HRID 1658096Notes

Reaction equation

HRID 1658096 reaction equation
[CH3:1][NH:2][C:3]1[C:4](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:5](O)=[O:6].[CH3:12][CH2:13][OH:14]>>[OH:6][C:5]1[C:4]2[C:3](=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:2]([CH3:1])[C:13](=[O:14])[CH:12]=1

Participants

3

Reactant 2

HCID 702EthanolHCID 67069N-Methylanthranilic acid

Product 1

HCID 546864364-Hydroxy-N-methylcarbostyril

Procedure

This was prepared from N-methyl anthranilic acid (22.04g. 0.146 mole) as described in example 30a., m.p. (EtOH) 270°-273°C. (Found; C, 68.59; H, 5.44; N, 7.73; C10H9NO2 requires; C, 58.56; H, 5.18; N, 8.00%).

Sources & evidence

ORD record
ord-60c989d9ad1c43e6aa257250b3924295
Source dataset
uspto-grants-1976_06
Patent number
US03962445

Reaction notes

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