Benzoyl Peroxide → HCID 12370782, compound

HRID 1658145Notes

Reaction equation

HRID 1658145 reaction equation
[Br:1]N1C(=O)CCC1=O.[CH3:9][C:10]1[CH:24]=[CH:23][C:13]2[N:14]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[O:16][C:12]=2[CH:11]=1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:1][CH2:9][C:10]1[CH:24]=[CH:23][C:13]2[N:14]=[C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[O:16][C:12]=2[CH:11]=1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 123707806-Methyl-2-phenyl-1,3-benzoxazole

Product 1

HCID 12370782HCID 12370782, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

N-Bromosuccinimide (25.9 gm) was added to a cold solution of 6-methyl-2-phenylbenzoxazole (30 gm) in carbon tetrachloride (250 ml). Benzoyl peroxide (500 mg) was added and the mixture was heated under reflux for 3 hr. in the presence of u.v. light. The solid residue was filtered off. The filtrate was evaporated down slightly, treated with carbon and allowed to cool. The crystals which were formed were recrystallised from benzene to yield 6-bromomethyl-2-phenylbenzoxazole, m.p. 162°C.

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 3 hr
  3. filtrationThe solid residue was filtered off
  4. customThe filtrate was evaporated down slightly,
  5. additiontreated with carbon
  6. temperatureto cool
  7. customThe crystals which were formed
  8. customwere recrystallised from benzene

Sources & evidence

ORD record
ord-b52987d3108045ed9fabb90b0a07b72a
Source dataset
uspto-grants-1976_06
Patent number
US03962452

Reaction notes

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