反应详情

A slurry of 12.0 g of 4-chlorobenzhydrylamine hydrochloride in 23 ml of O-methylcaprolactim was allowed to stand at room temperature for 3 days and was stirred occasionally with a glass rod. At first, the mixture became nearly homogeneous and then it began to solidify. Small amounts of anhydrous ethanol were added to keep the mixture in a stirrable slurry. The mixture was then cooled, the solid was collected and washed with ether and was recrystallyzed twice from methanol-acetone to give 11.7 g of the title compound, m.p. 238°-240°C. The identity of the compound was confirmed by micro-analysis, infrared and ultraviolet spectra.

1. temperatureThe mixture was then cooled
2. customthe solid was collected
3. washwashed with ether